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This page contains simplified steps for building quickly .

If you downloaded the virtual machine disk image, skip this step.

BRL-CAD uses the CMake build system and may be built with most compilers, so first step is to download and install CMake . If needed, compiling from their source distribution is actually very easy.

If you're on a Mac or Windows, you're good to go. For Linux, BSD, and other package-managed systems, you'll want to install a few things.

If you downloaded the virtual machine disk image, run this to make sure you have the latest sources:

For everyone else, we recommend obtaining the latest sources from our repository:

If you run into trouble, snapshot release sources may also be obtained from Sourceforge .

Next, set up a build directory and configure your compilation:

By default, our build enforces code standards that will halt on trivial issues, so we recommend turning off that strict behavior for your first compile. By default, it will also search your system for dependencies, but this can be complicated so we tell the build to use our bundled versions. When you graduate to doing development, you'll want to change the build type to -DCMAKE_BUILD_TYPE=Debug instead of Release.

BRL-CAD source files contain an INSTALL file with more detailed instructions if you want to customize the build.

You're good to go, now it's time to compile:

Compilation can take anywhere from a couple minutes to an hour depending on your hardware. If you had a quad-core CPU, you might run '"make -j4" to request compiling in parallel.

If the build fails, re-run make while capturing all output to a log: make > build.log 2>1 Please report any build failures.

You don't have to install to run BRL-CAD. You can just run the binaries you just finished compiling. They are in the brlcad/.build/bin directory. There are 400+ tools in BRL-CAD. Here's a couple to get started:

The first command will evaluate your system performance. If you made a Release build, please submit your benchmark results to benchmark at brlcad dot org.

The second command runs the main graphical interface. Be sure to check out the extensive Documentation and Main_Page for tutorials.

The third runs our newer graphical interface that is under development.

Help make BRL-CAD better! There are many ways you can contribute to open source and you don't need to be an experienced programmer. We do need software developers, but we also need artists, writers, designers, and managers.

Small brands have been beating big packaged-goods players for years, creating an insatiable appetite for acquisitions. Kao Brands is the latest into the game, buying high-end Oribe Hair Care for an undisclosed sum on Wednesday. It will become part of Kao's Salon Division. That follows Unilever's acquisition of Schmidt's Naturals deodorants last week, its acquisition of Sundial Brands last month, and Procter Gamble Co.'s acquisition of the Native natural deodorant brand last month. Expect more next year, as U.S. companies, flush with more cash from the tax cut, look for new ways to spend their money.

The Grocery Manufacturers Association is running low on members, and not because they're all being acquired. Unilever and Tyson Foods joined a growing number of big players who aren't re-upping in the primary trade association that represents packaged-goods players, Politico reports. Nestle , Mars, Dean Foods and Campbell Soup Co. are among others that have left. Politico attributes the defections to disagreements with the GMA's aggressive opposition to such things as labeling foods with genetically-modified-organism ingredients. Unilever didn't say so much, but did note in a statement that it wants to focus on advocacy aligned with its Sustainable Living Plan.

As if Amazon hasn't dominated 2017 enough (Alexa, order the congratulatory champagne), a new report suggests its private labels, which the Seattle-based ecommerce giant has been ramping up, saw blockbuster growth this year. Such growth was led by AmazonBasics, which generated $400 million in estimated sales, year-to-date, or 85 percent of Amazon's total private brand stable, according to data tracker One Click Retail. Baby wipes, in particular, nearly doubled in sales year-over-year to nearly $15 million in 2017. That's a lot butt cleaning.

JC Penney is going after post-holiday shoppers with a new "Find the One" campaign. Running from Dec. 29 through Jan. 1, the promotion, which was created in-house, assigns a personality profile to each pair of pants, taking a cue from modern dating sites. For jeggings, for example, a promo reads, "On a typical Friday night I am…Always up for anything. Pair me with sneakers, booties so much more." The struggling retailer is also offering buy one, get one-type offers and reward points for loyal customers. "Research shows that once a customer finds a specific pant fit they love, their brand loyalty increases tremendously," wrote a JC Penney spokeswoman via email. After recent sales declines that led to lowered financial expectations, JC Penney is desperate for the perfect match.

Ally Financial has tapped Vice for a new content series focused around the topic du jour—millennials and money. Called "The Right Start," the digital series covers the generation's untraditional pursuit of American dreams like buying a home, starting a family and purchasing a car. The content will be pushed out on Ally and Vice sites and social media channels.

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Abstract

Objective: The Androgen Excess Society (AES) charged a task force to review all available data and recommend an evidence-based definition for polycystic ovary syndrome (PCOS), whether already in use or not, to guide clinical diagnosis and future research.

Objective:

Participants: Participants included expert investigators in the field.

Participants:

Evidence: Based on a systematic review of the published peer-reviewed medical literature, by querying MEDLINE databases, we tried to identify studies evaluating the epidemiology or phenotypic aspects of PCOS.

Evidence:

Consensus Process: The task force drafted the initial report, following a consensus process via electronic communication, which was then reviewed and critiqued by the AES Board of Directors. No section was finalized until all members were satisfied with the contents and minority opinions noted. Statements that were not supported by peer-reviewed evidence were not included.

Consensus Process:

Conclusions: Based on the available data, it is the view of the AES Task Force on the Phenotype of PCOS that there should be acceptance of the original 1990 National Institutes of Health criteria with some modifications, taking into consideration the concerns expressed in the proceedings of the 2003 Rotterdam conference. A principal conclusion was that PCOS should be first considered a disorder of androgen excess or hyperandrogenism, although a minority considered the possibility that there may be forms of PCOS without overt evidence of hyperandrogenism but recognized that more data are required before validating this supposition. Finally, the task force recognized, and fully expects, that the definition of this syndrome will evolve over time to incorporate new research findings.

Conclusions:
Issue Section:

THE DISORDER THAT eventually would be known as the polycystic ovary syndrome (PCOS) was initially described by Stein and Leventhal in 1935 ( 1 ). There is little disagreement that PCOS should be considered a syndrome, i.e. a collection of signs and features, in which no single test is diagnostic. In essence, the whole (or global assessment) is greater than the sum of the individual features. However, establishing a clear, contemporaneous, and evidence-based definition for this syndrome has important clinical and investigational implications. Nonetheless, the definition of PCOS has continued to generate significant controversy ( 2 4 ).

Clinically, diagnosing a woman as having PCOS implies an increased risk for infertility, dysfunctional bleeding, endometrial carcinoma, obesity, type 2 diabetes mellitus, dyslipidemia, hypertension, and possibly cardiovascular disease ( 5 ). Furthermore, it has important familial implications, principally, but not exclusively, for her sisters and daughters ( 6 8 ). Finally, a diagnosis of PCOS may mandate life-long treatments, e.g. the use of insulin sensitizers, and may negatively affect her ability to access health care coverage, principally in capitalistic markets. Consequently, the diagnosis of PCOS should not be assigned lightly, and diagnostic criteria should be based on robust data.

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